Inflammation Signals
KPV is studied for how it may quiet chemical messages that drive inflammation.
Cellular Response Research
KPV — 10 mg
10 mg / vial
KPV is a three-amino-acid fragment of the natural hormone alpha-MSH. Researchers use cell and animal models to study how it moves through surface cells and affects signals linked with inflammation, including in protective linings.
€40,00
Research only
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Bac Water Needed
For in-vitro laboratory research only. Not for human or veterinary use.This information is provided for scientific and educational product context only. It does not describe or recommend human use, veterinary use, diagnosis, treatment, prevention, dosage, administration, or clinical application.
At a glance
What It Does in the Body
Digestive Lining
Researchers study how KPV enters cells lining the intestines and affects their response to irritation.
Immune Signals
It may affect messages released by immune cells during inflammation.
Surface Repair
Animal research has examined how KPV may affect recovery of protective surface cells, including the eye's outer layer.
NECESSARY RESEARCH EQUIPMENT
Bacteriostatic Water
Available separately for laboratory use.
Bacteriostatic Water — 3 mL
€10,00
Bacteriostatic Water — 10 mL
€15,00
Document available
Product document
Analytical documentation
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Full research details
Full research details for KPV
Read the supporting laboratory, animal and human research. This section does not provide instructions for human or veterinary use, diagnosis, treatment, prevention, dosage or administration.
What this compound is
KPV is a small peptide made from lysine, proline and valine. It matches the end section of alpha-melanocyte-stimulating hormone, often shortened to alpha-MSH. Researchers use KPV to study how this small fragment behaves without the full hormone. Current sources focus on cell transport, inflammatory signals and protective surface cells.
MaterialThree-amino-acid peptide fragment
Main research areaEpithelial and inflammatory signalling
Evidence availableCell and animal model research
Catalogue categoryCellular Response Research
How It Works
Normal target and function. KPV is studied in relation to PepT1, a transporter that normally moves small peptides across some epithelial cells. Researchers also measure NF-kB and cytokines, which are normal signalling systems cells use to coordinate inflammatory responses. A single direct KPV receptor has not been confirmed.
One research question is how KPV crosses epithelial cells, the cells that form surfaces and barriers. Intestinal studies have examined a transporter called PepT1, which moves small peptides into cells. Researchers then measure signals such as NF-kB and cytokines, which help coordinate inflammation. Other work uses eye-surface injury models. Researchers also check whether the fragment remains intact during each experiment.
Peptide transport
Cell studies examine whether PepT1 moves KPV across intestinal surface cells.
Inflammatory messages
Researchers measure NF-kB and cytokines, signals involved in cell responses to stress.
Surface-cell biology
Work includes epithelial cells that form protective layers in the intestine and cornea.
Fragment research
KPV is studied as a small part of alpha-MSH, not as the complete hormone.
Laboratory and Animal Research
Intestinal cell work has reported PepT1-dependent transport and changes in inflammatory signals. Animal eye-surface and inflammation models have reported changes in epithelial endpoints after controlled injury. These are preclinical observations and do not demonstrate an effect in people.
Measurements used in these studies
- PepT1-dependent movement of KPV into cells
- Inflammatory signals measured after a controlled challenge
- Movement and recovery markers in epithelial cells
- Differences between KPV and the full alpha-MSH molecule
Research Evidence
Human evidence
The linked evidence comes from intestinal cells and animal surface-tissue models. It does not show whether KPV produces the same signals or any noticeable effect in people.
Adverse effects
Reliable human safety information for KPV is not available, so a product-specific adverse-effect list cannot be supported.
| Evidence type | What was studied | How much evidence | What this means |
|---|---|---|---|
| Laboratory research | Intestinal cell models | Preclinical | Studies examined peptide transport and changes in inflammatory signals. |
| Animal research | Corneal and inflammation models | Preclinical | Animal work measured surface-cell endpoints after controlled injury. |
| Human research | Controlled clinical studies | Not established | The sources linked on this page do not contain meaningful controlled human research for KPV. |