Calmness and Stress
Selank is studied for signals connected to stress and anxious feelings. Some human research reported that people felt calmer.
Neurobiological Signaling Research
Selank — 10 mg
10 mg / vial
Selank is a synthetic seven-amino-acid peptide related to tuftsin. Researchers study nerve-cell communication and signals linked with GABA, calmness, stress and attention.
€45,00
Research only
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Bac Water Needed
For in-vitro laboratory research only. Not for human or veterinary use.This information is provided for scientific and educational product context only. It does not describe or recommend human use, veterinary use, diagnosis, treatment, prevention, dosage, administration, or clinical application.
At a glance
What It Does in the Body
Anxiety-Related Feelings
Small human research measured reductions in anxious feelings and mental tension.
Attention Under Stress
Researchers study whether Selank helps the brain maintain attention when stress makes thinking harder.
Brain Communication
It may influence chemical messages that help calm overly active brain signals.
NECESSARY RESEARCH EQUIPMENT
Bacteriostatic Water
Available separately for laboratory use.
Bacteriostatic Water — 3 mL
€10,00
Bacteriostatic Water — 10 mL
€15,00
Full research details
Full research details for Selank
Read the supporting laboratory, animal and human research. This section does not provide instructions for human or veterinary use, diagnosis, treatment, prevention, dosage or administration.
What this compound is
Selank is a synthetic seven-amino-acid peptide related to a natural immune peptide called tuftsin. Research examines molecular signals in nerve-cell models, including genes connected with GABA signalling. GABA is one of the nervous system's main inhibitory messengers. One small human comparison also measured anxiety and fatigue-related symptoms in people with diagnosed disorders.
MaterialSynthetic seven-amino-acid peptide
Main research areaGABA-related neural signalling
Evidence availableCell, animal and limited human comparison research
Catalogue categoryNeurobiological Signaling Research
How It Works
Normal target and function. Selank has no single confirmed human receptor target. Research follows genes related to GABA, a natural chemical messenger that reduces activity in many nerve circuits, as well as other neural and immune signalling networks. A change in gene activity is not the same as a change in mood or behaviour.
GABA helps reduce activity in many nerve circuits. Researchers have studied whether Selank changes the expression of genes linked with GABA receptors and other neural signalling systems. Some experiments use cultured human-derived cells. Separately, a 62-person comparison used anxiety scales, clinical ratings and fatigue-related symptoms.
GABA system
Studies examine genes connected with a major inhibitory messenger in the nervous system.
Gene expression
Researchers measure which signalling genes become more or less active in a model.
Cell models
Some work uses cultured cells to compare molecular responses under fixed conditions.
Tuftsin relation
Selank is structurally related to a natural peptide, but it is a separate synthetic compound.
Laboratory and Animal Research
Cultured neuronal cells and animal tissue studies have reported changes in GABA-related and other signalling genes. These results are preclinical and model-dependent; they do not demonstrate an anxiety, cognition or wellbeing effect in people.
Measurements used in these studies
- Genes linked with GABA receptors and neural signalling
- Molecular responses in cultured neuronal cell models
- How results differ between cell systems and animal tissue
- Which proposed mechanisms have direct experimental support
Research Evidence
Human evidence
Cultured cells and animal tissue cannot show what a person would feel or experience. The linked sources do not support a dependable controlled human conclusion for Selank.
Adverse effects
The available source set does not establish a reliable Selank adverse-effect pattern in people.
| Evidence type | What was studied | How much evidence | What this means |
|---|---|---|---|
| Laboratory research | Cultured neuronal cells | Preclinical | Gene-expression and signalling changes have been reported in controlled cell systems. |
| Animal research | Neural tissue and behaviour models | Preclinical | Animal findings are discussed in the literature but do not establish human effects. |
| Human research | Anxiety and fatigue-related symptom scales | Early and limited | A 62-person comparison reported changes on anxiety and fatigue-related measures. It was small and not a large independent placebo-controlled trial. |
Research references
Selank and GABA-related gene activity
PubMed, 2016
Preclinical research on genes involved in neural signalling.
Selank in an IMR-32 cell modelPubMed, 2017
Laboratory comparison of molecular responses in cultured cells.
Review of Selank molecular researchPubMed, 2018
Overview of proposed mechanisms and preclinical evidence.
Selank anxiety and fatigue comparisonPubMed, 2008
Small human study using anxiety scales, clinical ratings and fatigue-related symptoms.