Facial Movement Lines
SNAP-8 is designed to affect signals linked with repeated facial movement. Researchers study whether this may soften the look of expression lines.
Dermal and Matrix Research
SNAP-8 — 10 mg
10 mg / vial
SNAP-8 is a synthetic eight-amino-acid peptide. Researchers study its link with SNAP-25, which helps cells release chemical messages, along with its stability and movement through skin models. Results from finished cosmetic formulas do not prove the same effect for this raw material.
€40,00
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For in-vitro laboratory research only. Not for human or veterinary use.This information is provided for scientific and educational product context only. It does not describe or recommend human use, veterinary use, diagnosis, treatment, prevention, dosage, administration, or clinical application.
At a glance
What It Does in the Body
Skin Appearance
It is used in skin research focused on wrinkles, texture and hydration. Results depend on the complete product formula.
Skin Delivery
Researchers study whether the peptide can pass through the outer skin and reach the area where it is intended to act.
Human results for isolated SNAP-8 remain limited.
Full research details
Full research details for SNAP-8
Read the supporting laboratory, animal and human research. This section does not provide instructions for human or veterinary use, diagnosis, treatment, prevention, dosage or administration.
What this compound is
SNAP-8, also called acetyl octapeptide-3, is an eight-amino-acid synthetic peptide used in laboratory and cosmetic-formulation research. Its design is discussed in relation to SNAP-25, a protein involved in the SNARE complex that helps cells release chemical messengers. Evidence about the raw peptide, skin delivery and finished formulations must be kept separate because they are not interchangeable.
MaterialAcetylated eight-amino-acid peptide
Main research areaSNARE-related and skin-formulation research
Evidence availableMostly laboratory and formulation evidence
Catalogue categoryDermal and Matrix Research
How It Works
Normal target and function. The SNARE protein complex normally allows small vesicles inside a cell to join the cell membrane and release chemical messengers. SNAP-25 is part of that machinery. SNAP-8 was designed as a short peptide related to SNAP-25, but direct target engagement in human skin has not been established.
The SNARE complex is a group of proteins that helps small packages inside a cell join with the cell membrane and release their contents. SNAP-25 forms part of that machinery. Researchers examine peptide fragments related to this system and test whether they influence protein interactions in laboratory setups. Skin-formulation studies must also ask whether a peptide crosses the outer skin layer and remains stable. A formulation result does not establish an effect for this laboratory vial.
SNARE machinery
This protein system helps cells release chemical messengers from small internal packages.
SNAP-25 relation
The peptide design is discussed in relation to one part of the SNARE complex.
Skin delivery
Formulation research asks whether peptides can cross the skin barrier and remain intact.
Formulation limits
Results depend on the complete formulation, not only the name of one ingredient.
Laboratory and Animal Research
Laboratory and formulation work has examined SNARE-related protein interactions, peptide stability and movement through skin-barrier models. Results depend on the complete formulation and delivery system. They do not prove a wrinkle, muscle or medical effect for this raw reference material.
Measurements used in these studies
- Protein interactions linked with the SNARE complex
- Peptide stability in controlled test conditions
- Movement through laboratory skin-barrier models
- Differences between a raw material and a finished cosmetic formulation
Research Evidence
Human evidence
Reports about complete cosmetic formulations cannot be treated as controlled human evidence for raw SNAP-8. The linked research does not establish what this vial would do in a person.
Adverse effects
A reliable human safety profile for raw SNAP-8 is not available from the current sources.
| Evidence type | What was studied | How much evidence | What this means |
|---|---|---|---|
| Laboratory research | Protein and skin-barrier models | Limited and model-specific | Studies examine related peptide mechanisms, stability and permeability. |
| Animal research | SNAP-8-specific evidence | Not established here | The sources linked on this page do not provide a clear animal evidence base for this exact listing. |
| Human research | Cosmetic formulation studies | Limited | Broader formulation reports do not establish a clinical or product-specific outcome for this raw material. |
Limits of the Evidence
- Evidence about SNAP-25 biology is not automatically evidence about SNAP-8.
- Skin delivery and stability depend on the complete formulation and test method.
- No medical effect or finished-cosmetic performance is established for this product.
Research references
The SNAP-25 protein family
PubMed, 2018
Background on the cellular machinery related to the peptide design.
Review of topical peptidesPubMed, 2016
Formulation context and limits; not proof for this laboratory product.
Peptide skin permeability researchPubMed, 2022
Study of delivery and formulation-dependent performance.
Multi-ingredient wrinkle patch studyPubMed, 2024
Human microneedle study containing acetyl octapeptide-3 plus other active ingredients.
Multi-peptide microneedle studyPubMed, 2020
Human skin measurements from a formulation containing several bioactive ingredients.